The transatlantic relationship between Europe and the United States is and will remain a crucial element to enhance global stability and economic prosperity, not least in this period of international polycrisis and resultant shifts in global dynamics. The close cooperation between Europe and the US, including relations within multilateral organizations such as NATO, is built on a common history and shared set of democratic values that have shaped collective foreign policy across areas including security, energy, technology cooperation, and Ukraine. As the necessity for close cooperation and conflict resolution continues to grow, what lies ahead for the EU, as well as non-member European states, and the Transatlantic relationship? What is the role of the private sector and civil society in shaping the international security agenda?