Escalating security challenges driven by the expansion of transnational organized crime have become one of the most serious political and economic risks facing democracies today. Criminal networks erode governance, undermine the rule of law, weaken public trust, and deter investment, with lasting consequences for economic stability and democratic resilience. This panel will examine how insecurity reshapes political landscapes across regions and explore coordinated strategies to strengthen institutions and address both immediate threats and the structural vulnerabilities that criminal groups exploit.